The RAT ANTI MOUSE CDw199 Antibody from MyBioSource.com is a Rat Monoclonal antibody to CC-CKR-9, CCR9, D6, and ACKR2. This antibody recognizes Mouse antigen. The RAT ANTI MOUSE CDw199 Antibody has been validated for the following applications: Flow Cytometry.
Description
Rat anti Mouse CDw199 antibody, clone 9B1 detects mouse chemokine receptor 9 (CCR9), also known as CDw199. CCR9 is a seven transmembrane protein which is a member of the beta chemokines receptor family. CCR9 is expressed in thymus and small intestine, and mediates the recruitment and development of thymocytes in response to CCL25; the only known ligand of CCR9. CCR9 is an alternative co-receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described. Clone 9B1 blocks CCL25-induced Ca2+ release, attenuating inflammation in a murine model of chronic ileitis when given in early disease stages